Genetic polymorphisms in sepsis
نویسندگان
چکیده
منابع مشابه
Genetic Polymorphisms and Sepsis in Premature Neonates
Identifying single nucleotide polymorphisms (SNPs) in the genes involved in sepsis may help to clarify the pathophysiology of neonatal sepsis. The aim of this study was to evaluate the relationships between sepsis in pre-term neonates and genes potentially involved in the response to invasion by infectious agents. The study involved 101 pre-term neonates born between June 2008 and May 2012 with...
متن کاملGenomic polymorphisms in sepsis.
OBJECTIVE This article aims to review all relevant genetic polymorphism studies that may contribute to the pathogenesis of sepsis with emphasis on polymorphisms of the innate immunity, pro- and anti-inflammatory cytokines, and coagulation mediators. DATA SOURCE Published articles reporting on studies of associations between genetic polymorphisms, sepsis, septic shock, and other relevant infec...
متن کاملGenetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy.
Genetic epidemiologic studies suggest a strong genetic influence on the outcome from sepsis, and genetics may explain the wide variation in the individual response to infection that has long puzzled clinicians. Several candidate genes have been identified as important in the inflammatory response and investigated in case-controlled studies, including the tumor necrosis factor (TNF)-alpha and TN...
متن کامل972Impact of Genetic Polymorphisms on the Risk of Sepsis in Premature Neonates
Neonates Susanna Esposito, MD; Alberto Zampiero; Lorenza Pugni; Silvia Tabano; Claudio Pelucchi; Beatrice Ghirardi; Leonardo Terranova; Monica Miozzo; Fabio Mosca; Nicola Principi; Pediatric Highly Intensive Care Unit, University Milan, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; Neonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Uni...
متن کاملGenetic polymorphisms in Drosophila
In a population evolving by gradual change, the amount of genetic variation is important because the rate of evolution is absolutely limited by the degree of genetic variability. Various forces of evolution such as natural selection, random genetic drift and migration operate on genetic variability which provides the raw material for evolution. Thus the rate of evolution is absolutely limited b...
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ژورنال
عنوان ژورنال: Nihon Kyukyu Igakukai Zasshi
سال: 2013
ISSN: 1883-3772,0915-924X
DOI: 10.3893/jjaam.24.1